Folia Parasitologica, vol. 62 (2015)

Folia Parasitologica 62:066 (2015) | DOI: 10.14411/fp.2015.066

The prevalence of anti-Toxoplasma gondii antibodies in stutterers is higher than in the control group

Tuncay Çelik1, Cem Gökçen2, Özgür Aytaº3, Aysima Özçelik4, Mustafa Çelik5, Nurdan Çoban2
1 Department of Parasitology, Faculty of Medicine, Adiyaman University, Adiyaman, Turkey;
2 Department of Child and Adolescent Psychiatry, Medicine Faculty of Gaziantep University, Gaziantep, Turkey;
3 Malatya State Hospital, Department of Psychiatry, Malatya, Turkey;
4 Department of Pediatric Neurology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey;
5 Department of Psychiatry, Faculty of Medicine, Adiyaman University, Adiyaman, Turkey

The purpose of this study was to investigate the possible relationship between Toxoplasma gondii (Nicolle et Manceaux, 1908) and stuttering. We investigated the seropositivity rate for anti-T. gondii IgG and antibodies by enzyme-linked immunosorbent assay (ELISA) in stuttering children to ascertain a possible relationship between T. gondii infection and stuttering. We selected 65 stuttering children and 65 control children (non-stutterers) to investigate the seropositivity rate of anti-T. gondii antibodies by ELISA. Cranial magnetic resonance imaging (MRI) and scalp electroencephalography (EEG) were also performed in stuttering children. The seropositivity rate of anti-T. gondii IgG antibodies among stuttering children (28%) was significantly higher than in control group (5%; p = 0.001). No abnormality was detected in cranial MRI's of stutttering children and their EEG recordings were also normal. There was no significant difference in seropositivity rate regarding age, genders and residence area. The association between seroprevalence of infection with T. gondii and stuttering may be due to hyperdopaminergic state in brains of patients who are T. gondii-seropositive. Thus, there might be a causal relationship between toxoplasmosis and stuttering.

Keywords: toxoplasmosis, stuttering, enzyme-linked immunosorbent assay (ELISA), electroencephalography (EEG), magnetic resonance imaging (MRI)

Received: May 18, 2015; Accepted: December 15, 2015; Published online: December 16, 2015


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